The authors document the cytological features on fine-needle aspiration cytology of a chondroblastoma which appeared as a lytic lesion in the. Chondroblastoma is an uncommon benign cartilage producing neoplasm with a characteristic epiphyseal location. This report documents the. Chondroblastoma is a rare primary bone tumor of young people .. Fine needle aspiration cytology of chondroblastoma of bone. Cancer.

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The multinucleated giant cells are a constant cyotlogy feature of smears from chondroblastoma. Fine needle aspiration cytology of chondromyxoid fibroma: Chondrobastoma in fine needle aspirates. Tumors of bone and cartilage. Clinically the differential diagnoses included aneurysmal bone cyst and giant cell tumor of bone. No mitotic figures were seen.

Jaffe HL, Lichtenstein L.

Schajowicz F, Gallardo H. J Foot Ankle Surg ; Although aspiration cytology is very convenient and reliable method for the rapid diagnosis of bone lesions, the failure rate is high.

An year-old-female presented with pain in left leg for last 1-month and progressively increasing swelling around the knee joint for last 15 days. chomdroblastoma

The radiologic appearance and cytlogy diagnosis in both cases are discussed. Grossly, the specimen consisted of multiple irregular grey-brown tissue bits with areas of hemorrhage.


The chondroid and myxoid elements form the irregular fragments of matrix in the background.

BMC Musculoskelet Disord ;5: A Reinterpretation of the so-called calcifying or chondromatous giant cell tumor. The chondroblasts were distributed singly in smears, had round to oval nuclei with indentation and lobulation, and fine evenly distributed chromatin. Areas of increased cell density forming fibrous cap were noted at the periphery of lobules.

Cytologically histiocytes of LCH are like chondroblasts of chondroblastoma but not associated with any type of matrix production. The collective application of the knowledge of the cytomorphological features of this rare chondroblastomaa tumor would aid in accurate preoperative diagnosis even in the absence of typical clinical and radiologic presentations.

Cytological diagnosis of chondroblastoma: diagnostic challenge for the cytopathologist

The intramedullary cartilage tumors. There was no history of trauma.

She also gave history of trauma at the same site. Fine needle aspiration cytology. Chondromyxoid fibroma closely mimics chondroblastoma due to the presence of myxoid background substance, chondroid fragments and osteoclastic giant cells; however, its spindle-shaped or stellate, fibroblast-like tumour cells in contrast to the mononuclear cells of chondroblastoma with distinct cell borders, round-to-oval nuclei and dense eosinophilic cytoplasm help in differentiating these two entities.


Dispersed mononuclear chondroblasts demonstrate well-defined, deeply eosinophilic cytoplasm with centrally or eccentrically placed oval or round nuclei, with longitudinal grooves. Diagnostic cytological chondroblastoja of condroblastoma are sheet-like clusters of mononuclear cells, scattered osteoclast-like giant cells and focal chondroid matrix formation.

Report of two cases diagnosed by cytology.

Case Report: Cytological diagnosis of chondroblastoma: diagnostic challenge for the cytopathologist

Myxoid chondrosarcoma of sphenoid sinus and chondromyxoid fibroma of iliac bone: Daneshbod Y, Khademi B. One had swelling at the lower end of the femur, whereas in the other case the upper end of the tibia was involved. Radiograph showed a lytic cjondroblastoma in the head and upper shaft of the fibula. Ipsilateral inguinal lymphadenopathy chondroblwstoma not demonstrable. Individually lying chondroblasts with a distinct cell boundary, nuclear grooves, chodroid matrix and chicken-wire calcification are diagnostic cytological features of chondroblastoma and make FNA a prudent preoperative technique in the management of these patients.

Arch Pathol Lab Med ; Few fibroblast-like spindle cells were seen embedded in the myxoid matrix.